🔑 Key Learning
- Surgical emergency caused by infection of the flexor tendon sheath in the hand.
- Presents with the classic Kanavel’s signs.
- Requires urgent surgical intervention and antibiotics to prevent tendon necrosis and permanent hand dysfunction.
🧬 Pathophysiology
- Infection of the synovial sheath that surrounds the flexor tendons of the fingers.
- Most commonly due to penetrating trauma (e.g. bite, puncture wound), or haematogenous spread.
- Common pathogens: Staphylococcus aureus (including MRSA), Streptococci, and Gram-negative bacilli.
- Infection leads to increased pressure, vascular compromise, and potential tendon necrosis.
👀 Clinical Features
- Pain, swelling, and loss of function in the affected finger.
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Classically presents with Kanavel’s Four Cardinal Signs:
- Finger held in flexion
- Fusiform swelling (uniform swelling along the finger)
- Tenderness along the flexor tendon sheath
- Pain on passive extension of the digit
- May also be systemic signs: fever, malaise.

💊 Management
- Urgent referral to hand surgery/plastics team if Kanavel signs are present.
- Surgical irrigation and drainage of the tendon sheath is required to evacuate pus and decompress the sheath.
- Empirical IV antibiotics: Flucloxacillin or co-amoxiclav
📝 Exam Clues & Clinchers
- Penetrating trauma to finger followed by pain and fusiform swelling
- Classic Kanavel signs — especially pain on passive extension